Femme - Topical Progesterone Serum

What Femme Does For You

Femme delivers bio-identical progesterone directly through the skin, supporting the hormonal balance that underlies so many aspects of women’s health — from cycle regularity and PMS relief to sleep quality, mood, and skin vitality.

• Hormonal Balance — Delivers 20mg of USP bio-identical progesterone per 1mL dose — the same molecular structure as the progesterone your body produces naturally — to help restore and maintain healthy hormonal balance.
• Menstrual Comfort & PMS Relief — Progesterone plays a central role in regulating the menstrual cycle. Supplementing with bio-identical progesterone can ease PMS symptoms including cramping, bloating, breast tenderness, and mood swings, while supporting cycle regularity.
• Sleep & Relaxation — Progesterone has a natural calming effect on the nervous system, promoting deeper, more restful sleep and reducing hormonal anxiety — particularly during the luteal phase and perimenopause.
• Skin Health — The coconut-derived base moisturizes and nourishes skin while supporting transdermal absorption. Progesterone also supports skin elasticity and hydration at the cellular level.
• Optimal Transdermal Absorption — The coconut oil base (caprylic/capric triglyceride) is specifically chosen for its superior ability to carry active ingredients through the skin barrier, ensuring the progesterone reaches systemic circulation efficiently.
• Supports Perimenopause & Menopause Transition — As progesterone naturally declines with age, topical bio-identical progesterone can help ease the transition, supporting mood stability, sleep, and overall hormonal well-being.
• Clean & Pure Formula — Only four ingredients — all natural, all purposeful. No synthetic fillers, no unnecessary additives.

What’s Inside Femme

Progesterone per dose: 20mg | Dose volume: 1mL | Bottle size: 30mL (1 fl oz)

USP Bio-Identical Progesterone (Ultra-Micronized)

The active ingredient in Femme is USP-grade bio-identical progesterone — meaning it is chemically identical to the progesterone produced by the human body, derived from plant sources (typically wild yam or soy) and processed to match the exact molecular structure of endogenous progesterone. Ultra-micronization reduces the particle size to maximize surface area and improve transdermal absorption and bioavailability. Each 1mL dose delivers a precise 20mg of progesterone.

Caprylic/Capric Triglyceride (from Coconut)

A premium, skin-compatible carrier oil derived from coconut. Caprylic/capric triglyceride is widely used in pharmaceutical and cosmetic formulations for its exceptional ability to penetrate the skin barrier and carry active ingredients into systemic circulation. It is lightweight, non-greasy, and deeply moisturizing — making it ideal for a topical hormone serum.

Dimethyl Isosorbide (DMI)

A pharmaceutical-grade penetration enhancer that significantly improves the transdermal delivery of active ingredients. DMI helps the progesterone molecules pass through the skin’s outer layers more efficiently, increasing the amount of progesterone that reaches the bloodstream per dose.

Vitamin E

A natural antioxidant that protects the formula from oxidation and supports skin health. Vitamin E also has its own hormonal support properties and helps maintain the stability and potency of the progesterone in the serum.

Directions for Use

Apply 1mL (one full dropper) to clean skin 1–2 times per day, or as directed by your healthcare provider. The calibrated dropper makes it easy to measure your exact dose.

• Apply 1mL to thin-skinned areas for best absorption: inner wrists, inner arms, neck, chest, or inner thighs
• Rotate application sites daily to prevent receptor saturation
• Gently massage into skin until fully absorbed
• Use 1–2 times per day as directed — morning and/or evening
• For cycle-based use: apply during the luteal phase (days 14–28) and take a break during menstruation — consult your healthcare provider for personalized guidance
• Store in a cool, dry place away from direct sunlight and heat
• Keep out of reach of children

Pro Tips:

• Apply to freshly cleansed skin before other skincare products for maximum absorption
• Rotating application sites is important — using the same spot repeatedly can reduce absorption efficiency over time
• Consistency is key — hormonal support works best with regular, daily use over several weeks
• If you are using other hormone therapies or medications, consult your healthcare provider before use

Frequently Asked Questions

Q: What is bio-identical progesterone and how is it different from synthetic progestins?
A: Bio-identical progesterone has the exact same molecular structure as the progesterone your body produces naturally. Synthetic progestins (used in many birth control pills and HRT formulations) are chemically different and can have different effects and side effect profiles. Bio-identical progesterone is generally considered to have a more favorable safety profile and is better tolerated by most women.

Q: Who is Femme for?
A: Femme is designed for women experiencing symptoms of progesterone deficiency or hormonal imbalance — including PMS, irregular cycles, sleep disruption, hormonal anxiety, and perimenopausal symptoms. It is also used by women seeking natural hormonal support as an alternative or complement to conventional HRT.

Q: How much progesterone is in each dose?
A: Each 1mL dose delivers 20mg of USP bio-identical progesterone. The calibrated dropper allows you to measure your dose precisely.

Q: Where should I apply the serum?
A: Apply to thin-skinned areas with good blood flow — inner wrists, inner arms, neck, chest, or inner thighs. Rotate application sites daily to maintain consistent absorption.

Q: How long before I notice results?
A: Many women notice improvements in sleep and mood within the first 1–2 weeks. Menstrual cycle benefits typically become more apparent after 1–2 full cycles of consistent use.

Q: Can I use Femme if I’m on other hormone therapies?
A: If you are currently using any hormone therapy, birth control, or prescription medications, please consult your healthcare provider before adding Femme to your routine.

Q: When will my order ship?
A: Orders ship Monday through Friday with a 3 business day processing time. You will receive an email notification when your order ships.

Allergen Information: Femme contains caprylic/capric triglyceride derived from coconut. If you have coconut allergies or sensitivities, or are taking hormone-related medications, please consult your healthcare provider before use. Not intended for use during pregnancy or breastfeeding without medical supervision. Keep out of reach of children.