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MTHFR Daily + VARS® Glutathione Bundle — Methylation & Detox Stack

MTHFR Daily + VARS® Glutathione Bundle — Methylation & Detox Stack

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At A Glance Bundle: MTHFR Daily + VARS® Liposomal Glutathione | Brand: Physician Designed™
Products Included: MTHFR Daily Methylation Multivitamin (120 capsules, 30-day supply) + VARS® Liposomal Glutathione® (60 capsules, 30-day supply)
Form: Vegetable Capsules | Classification: Dietary Supplement Bundle
Designed For: MTHFR gene variants, methylation support, glutathione optimization, liver detox, and comprehensive cellular health
Key Ingredients: Methylfolate (5-MTHF as folinic acid calcium salt) • Methylcobalamin + Adenosylcobalamin (B12 800mcg, 33,333% DV) • Pyridoxal-5-Phosphate (B6) • Riboflavin-5-Phosphate (B2) • Zinc • Selenium • Magnesium Glycinate • N-Acetyl L-Cysteine • Alpha Lipoic Acid • Myo-Inositol • Choline • VARS® Liposomal Glutathione 275mg (active reduced GSH, stable 1+ year)
Key Benefits: Methylation Pathways • Liver Detoxification • Glutathione Optimization • Energy Metabolism • Brain & Mood Health • Immune Function • Antioxidant Defense • Cardiovascular Health (Homocysteine Regulation) • Skin Health • Anti-Aging • Stress Resilience • Healthy Cell Renewal • Nerve Function • DNA Repair Support
Complementary Products: VARS® SOD (cellular antioxidant defense) • Brite Brain (cognitive support) • VARS® Liposomal Vitamin C (glutathione regeneration)
Bundle Synergy: Methylation (MTHFR Daily) drives endogenous glutathione synthesis — VARS® Glutathione fills the gap while methylation pathways are restored. NAC in MTHFR Daily further supports glutathione recycling. Together they address the root cause, not just symptoms.
Free Of: GMOs • Gluten • Nuts • Dairy • Fish • Shellfish • Soy (VARS® Glutathione) | Made In: USA
Made By: Physician Designed™ | Science. Wellness. Purpose.

The Complete Methylation & Detox Foundation.

Methylation and glutathione are two of the most critical and interconnected systems in the human body — and most people are running deficient in both. MTHFR Daily provides the active, methylated vitamins your body needs to run its methylation pathways at full capacity. VARS® Liposomal Glutathione delivers the master antioxidant your liver needs to detoxify, protect cells, and clear the oxidative burden that impaired methylation leaves behind. Together, they form a complete, physician-designed foundation: methylation fuels glutathione production, and glutathione protects the cellular machinery that methylation depends on. This is the stack built for those who want to address the root — not just the symptoms.

Two Products. One Complete System.

MTHFR Daily — Methylation Multivitamin (120 Capsules)

MTHFR Daily is a comprehensive methylation multivitamin providing vitamins and minerals in their active, bioavailable forms — bypassing the MTHFR enzyme entirely. Key ingredients include:

  • Methylfolate (800mcg DFE as folinic acid calcium salt) — active folate that bypasses MTHFR conversion, 200% DV
  • Vitamin B12 (800mcg as adenosylcobalamin and hydroxocobalamin) — 33,333% DV; active B12 forms for immediate cellular use
  • Vitamin B6 (10mg as pyridoxal-5-phosphate) — active P5P form, 588% DV
  • Riboflavin B2 (50mg as riboflavin-5-phosphate) — active form, 3846% DV; essential MTHFR cofactor
  • Thiamine B1 (75mg as thiamine HCl) — 6250% DV
  • Zinc (2mg as zinc citrate), Selenium (75mcg), Magnesium (100mg as magnesium glycinate)
  • Alpha Lipoic Acid (25mg), Myo-Inositol (50mg), Choline (100mg), N-Acetyl L-Cysteine (100mg)
  • Full spectrum: Vitamin C, Niacin, Pantothenic Acid, Biotin, Iodine, Manganese, Chromium, Molybdenum

Serving Size: 4 Capsules | Servings: 30 | 120 Capsules Total | Other Ingredients: L-Leucine, vegetable capsule (hypromellose/HPMC, purified water)

VARS® Liposomal Glutathione — Master Antioxidant (60 Capsules)

VARS® Liposomal Glutathione delivers 275mg of clinically validated, stable glutathione per serving using a liposomal delivery system that protects it through digestion and delivers it directly to cells. Validated stable for 1+ year without oxidizing.

  • VARS® Liposomal Glutathione® — 275mg per serving (active, reduced GSH form; VARS® = Validated Absorbable, Reduced Stable)
  • Other Ingredients: Vegetable capsule, gum arabic, sunflower lecithin, sodium alginate, rice bran
  • Free of: GMOs, Gluten, Nuts, Dairy, Fish, Shellfish, Soy

Serving Size: 2 Capsules | Servings: 30 | 60 Capsules Total

What This Bundle Does For You

  • Supports Methylation Pathways — MTHFR Daily provides methylfolate and methylcobalamin in their pre-converted, active forms, bypassing the MTHFR enzyme bottleneck and restoring full methylation capacity regardless of genetic variant.
  • Optimizes Glutathione Production & Delivery — Methylation is the primary driver of endogenous glutathione synthesis. By restoring methylation, MTHFR Daily helps your body produce more glutathione naturally — while VARS® delivers additional liposomal glutathione directly to your cells.
  • Supports Liver Detoxification — Both methylation and glutathione are essential for liver phase I and phase II detoxification. This bundle provides comprehensive support for the liver’s ability to process and eliminate toxins, heavy metals, and harmful compounds.
  • Promotes Brain & Mood Health — Methylation drives neurotransmitter synthesis (serotonin, dopamine, norepinephrine). Glutathione protects neurons from oxidative damage. Together they support cognitive clarity, mood stability, and mental resilience.
  • Boosts Energy Metabolism — Active B vitamins support mitochondrial energy production; glutathione protects mitochondria from oxidative damage. The result is more efficient, sustained cellular energy.
  • Strengthens Immune Function — Both methylation and glutathione are critical for immune cell proliferation and function. This bundle provides dual-pathway immune support.
  • Antioxidant Defense — VARS® Glutathione neutralizes free radicals and regenerates vitamins C and E. NAC in MTHFR Daily further supports glutathione recycling. Together they provide comprehensive antioxidant coverage.
  • Regulates Homocysteine for Cardiovascular Health — Methylated B vitamins (B6, B12, folate) are the primary regulators of homocysteine — a key cardiovascular risk factor elevated by impaired methylation. Glutathione reduces oxidative stress on blood vessels.
  • Promotes Clear, Bright Skin — Glutathione inhibits melanin synthesis and reduces oxidative skin damage. Methylation supports healthy cell renewal and collagen synthesis.
  • Anti-Aging at the Cellular Level — Methylation regulates gene expression and DNA repair. Glutathione protects cellular structures from oxidative damage. Together they address two of the primary drivers of cellular aging.

Directions for Use

Both products are designed for consistent daily use. Take them together as your complete morning methylation and detox foundation.

  • MTHFR Daily: Take 4 capsules daily with food
  • VARS® Liposomal Glutathione: Take 2 capsules daily, with or without food
  • Best taken together in the morning to support energy, detox, and cognitive function throughout the day
  • Store both products in a cool, dry place away from direct sunlight and heat
  • Keep out of reach of children

Why They Work Better Together:

  • Methylation (via MTHFR Daily) is required for the body to synthesize glutathione endogenously — restoring methylation amplifies your body’s own glutathione production
  • VARS® Glutathione provides immediate exogenous glutathione while methylation pathways are being restored, filling the gap during the correction phase
  • NAC in MTHFR Daily supports glutathione recycling, extending the effectiveness of the VARS® Glutathione you’re supplementing
  • Consistent daily use of both products is essential — methylation and glutathione optimization are cumulative processes that build over weeks and months

Stack Further:

  • Add VARS® Liposomal Vitamin C — Vitamin C regenerates oxidized glutathione back to its active form, amplifying the antioxidant effect of VARS® Glutathione
  • Add VARS® SOD — SOD neutralizes the superoxide radicals that glutathione’s downstream enzymes then safely clear, completing the full intracellular antioxidant cycle
  • Add Brite Brain — for enhanced cognitive support alongside the brain health benefits of methylation restoration

Frequently Asked Questions

Q: Why do methylation and glutathione go together?
A: Methylation is the primary biochemical pathway through which the body synthesizes glutathione. When methylation is impaired — as it is in those with MTHFR variants — glutathione production is reduced, leaving cells vulnerable to oxidative damage and toxin accumulation. Restoring methylation with MTHFR Daily helps your body produce more glutathione naturally, while VARS® Glutathione provides immediate supplemental support. They are complementary, synergistic, and most effective when used together.

Q: Do I need to have an MTHFR gene variant to benefit from this bundle?
A: No — both products are beneficial for everyone. Methylated vitamins are more bioavailable for all people, and liposomal glutathione supports detoxification, immunity, and antioxidant defense regardless of genetic status. However, for those with confirmed MTHFR variants, this bundle is especially important.

Q: What’s included in this bundle?
A: One bottle of MTHFR Daily (120 capsules, 30-day supply at 4 capsules/day) and one bottle of VARS® Liposomal Glutathione (60 capsules, 30-day supply at 2 capsules/day).

Q: How long before I notice results?
A: Many users notice improvements in energy, mental clarity, and mood within 2–4 weeks of consistent daily use. Detoxification, immune, and skin benefits build over time with continued supplementation. Full methylation optimization typically takes several months.

Q: Are these products free of common allergens?
A: VARS® Liposomal Glutathione is free of GMOs, gluten, nuts, dairy, fish, shellfish, and soy. MTHFR Daily other ingredients are L-Leucine and vegetable capsule (hypromellose/HPMC, purified water). If you have specific allergen concerns, please consult your healthcare provider.

Q: When will my order ship?
A: Orders ship Monday through Friday with a 3 business day processing time. You will receive an email notification when your order ships.

Allergen Information: If you have any food allergies, sensitivities, are pregnant, nursing, or are taking medications, please consult your healthcare provider before use. Keep out of reach of children.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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j
john b. (United States)
great product!!

great product!!

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